Research Projects

The list below includes current research projects with which Center personnel are involved. MSU/CEHS faculty are in maroon.

Sponsor Title of Project Investigators
     
NIH/NIEHS Organophosphate-mediated Inhibition of Cholesteryl Ester Hydrolase
     
NIH/NIEHS Effect of Organophosphate Exposure on Cholesteryl Ester Hydrolase  
(R15 Administrative Supplement)

     
NIH/NIEHS Effect of Organophosphates on Cholesteryl Ester Hydrolase
(R15 Competitive Supplement)
     
NIH/NIEHS Molecular Biology of Mesocortical and Mesoaccumbens Dopamine Neurons               
     
NIH/NIEHS Regulation and Function of Nurrl in Adult Nigrostriatal Dopamine Neurons
     
 NIH/NIEHS The Role of Exposure to Bioaccumulative Organochlorine Compounds on the Occurence of Obesity and Type 2 Diabetes
     
NIH/NIEHS Effects of Exposure to Bioaccumulative Organochlorine Compounds on the Development of Obesity and Type 2 Diabetes  G.E. Howell, III, PI
     
EPA/STAR New Environmental Public Health Indicator Linking Organochlorine Compounds and Type 2 Diabetes
     
DoD/DTRA Synthesis and Assay of Novel Pyridinium Oximes with Potential Activity in the Central Nervous System for Reactivating Phosphorylated Acetylcholinesterase J.M. Gearhart, PI
J.E. Chambers
H.W. Chambers
M.K. Ross
     

Completed Research Projects

This list includes research projects completed within the last year.

 
DoD/DTRA Synthesis and Assay of Novel Pyridinium Oximes with Potential Activity in the Central Nervous System for Reactivating Phosphorylated Acetylcholinesterase J.M. Gearhart, PI
J.E. Chambers
H.W. Chambers
     
NIH/NIEHS Relationship of Blood Esterases, Pesticide Exposure and Cardiovascular Disease J.E. Chambers, PI
H.W. Chambers
J.A. Crow
M.K. Ross
R.W. Wills
     
NIH/NIEHS The Effect of a Mixture of Pesticides on the Rat Cardiac Proteome J.A. Crow, PI
     
DoD/DTRA Molecular Modeling to Develop Better Reactivators
     
EPA/STAR An Integrated Computational Framework for the Interpretation of Organophosphorus Pesticide Biomarkers
     
MSU/ORED Association of Plasma Organochlorine Levels with Cardiovascular Disease and Diabetes
     
MSU/CVM/ORGS Effect of Organochlorine Exposure on Adipose Tissue Insulin Sensitivity and Inflammatory Status
     
MSU/CVM/DBS Chemical Knockdown of Carboxylesterases

 

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