Publications (Last 3 Years)

Liu, Z., Yuan, C. and Pruett, S.B. (2011). Machine Learning Analysis of the Relationship between Changes in Immunological Parameters and Changes in Resistance to Listeria Monocytogenes: A New Approach for Systems Immunology.  J. Immunol. submitted.

Tan, W., Cooley, J. , Austin, F. , Lu, S. , Pruett, S.B., and Smith, L. (2011). Pre-clinical Toxicological Evaluation of Occidiofungin, a Unique Glyco-lipopeptide Antifungal. Antimicrobial Agents and Chemotherapy.  submitted.

von Maltzan, K. and Pruett, S.B. (2011).  Investigation of the role of TNF- alpha Converting Ezyme (TACE) in the inhibition of cell surface and soluble TNF-alpha production by acute ethanol exposure. PLoS One, Submitted.

Minny Bhatty, Basit L Jan, Wei Tan, Stephen B Pruett,  Bindu Nanduri (2011). Role of acute ethanol exposure and TLR4 in early events of sepsis in a mouse model. Alcohol.  In press.

Bhatty, M., Swiatlo, E., Pruett, S.B., Nanduri, B. (2011).  Alcohol abuse and Streptococcus pneumoniae infections: Consideration of Virulence Factors and Impaired Immune Responses.  Alcohol.  45: 523-539. link to full paper

Mitzi Glover, Bing Cheng, Xiaomin Deng, and Stephen Pruett (2011). The role of glucococorticoids in the immediate vs. delayed effects of acute ethanol exposure on cytokine production in a binge drinking model.  Int. Immunopharm. 11:755-761. link to full paper

Pruett, S.B., Tan, W., Sebastian, T., and Liu, D. (2010).  Innate immunity and inflammation in organ failure.  In, Comprehensive Toxicology 2nd Edition, Charlene A. McQueen, ed., Oxford Press.

Lockett, N., Boudreaux, C.E., Scott, V. L., Clay, B. T., Pruett, S.B., and Ryan, P.L.. (2010).  Expression of regulatory T cell (Treg) activation markers in endometrial tissues from early and late pregnancy in the feline immunodeficiency virus (FIV)-infected cat.  Placenta. 31(9):796-802. link to full paper

von Maltzan K., Pruett S.B. (2010) ELISA assays and alcohol: Increasing carbon chain length can interfere with detection of cytokines. Alcohol, doi:10.1016/j.alcohol.2010.08.010 link to full paper

Pruett, S.B., Fan, R., Cheng, B., Glover, M., Tan, W., and Deng, X. (2010). Innate immunity and inflammation in sepsis: mechanisms of suppressed host resistance in mice treated with ethanol in a binge drinking model.  Toxicol. Sci. doi: 10.1093/toxsci/kfq215. link to abstract

Pruett, S.B. and Fan, R. (2009). Ethanol inhibits LPS-induced signaling and
modulates cytokine production in peritoneal macrophages in an in vivo mouse model of binge drinking.  BMC Immunology.  10:49. link to full paper

Glover, M., Cheng, B., Fan, R., and Pruett, S.B. (2009). The Role of Stress Mediators in Modulation of Cytokine Production by Ethanol.  Toxicol. Appl. Pharmacol. 239:98-105. link to full paper

Pruett, S.B., Fan, R., Zheng, Q., and Schwab, C.  (2009). Patterns of Immunotoxicity Associated with Chronic as compared to Acute Exposure to Chemical or Physical Stressors and their Relevance with regard to the Role of Stress and with Regard to Immunotoxicity Testing.  Toxicol. Sci.. 109: 265-275. link to full paper

Pruett, S.B., Cheng, B., Fan, R., Tan, W., Sebastian, T. (2009). Oxidative stress and sodium methyldithiocarbamate-induced modulation of the macrophage response to lipopolysaccharide in vivo.  Toxicol. Sci. 109: 237-246. link to full paper

Oppenheimer, S.F., Fan, R., and Pruett, S.B. (2009).  A model for gene activation.  The Electronic Journal of Differential Equations. 17:197-206.

Kassim, S.H., Rajasagi, N.K., Ritz, B.W., Pruett, S.B., Gardner, E.M., Chervenak, R., and Jennings, S.R. (2009).  Dendritic cells are required for optimal activation of natural killer functions following primary infection with herpes simplex virus type-1 (HSV-1).  J. Virol., 83:3175-86. link to full paper 

Frequently cited publications from the Pruett laboratory:

Szabo, G., Dolganiuc,A., Dai, Q., and Pruett, S.B. (2007). Brief Review: Toll-Like Receptor 4, Ethanol, and Lipid Rafts: A New Mechanism of Ethanol Action with Implications for Other Receptor Mediated Effects.  J. Immunol.  178:1243-1249 (cited 38 times). link to full paper

Carson, EJ; Pruett, SB. 1996.  Development and characterization of a binge drinking model in mice for evaluation of the immunological effects of ethanol. Alcoholism-Clinical And Experimental Research  Volume: 20   Issue: 1   Pages: 132-138 (cited 59 times). link to abstract

Fuchs, Ba; Pruett, Sb.  1993.  Morphine Induces Apoptosis In Murine Thymocytes In-Vivo But Not In-Vitro - Involvement Of Both Opiate And Glucocorticoid Receptors. Journal Of Pharmacology And Experimental Therapeutics  Volume: 266   Issue: 1 Pages: 417-423  (Cited 84 Times). link to abstract

Padgett, E.L. and Pruett, S.B. (1992).  Assessment of nitrite production by human monocyte-derived macrophages.  Biochem. Biophys. Res. Commun.  186:775-781 (cited 107 times).